求解关于数字1～66中，以数字1开头的九位不重复排列组合，用空格符号隔开 竖向输出。

Following code took five and a half hours to write the result to a large TXT file which is more than 100GB !

from time import time
from itertools import combinations

upper   = 66
qty     =  9
lst     = list(range(2, upper+1))

start   = time()

with open("numbers.txt", "wt") as f:
    for items in combinations(lst, qty-1):
        f.write(' '.join(('1',) + tuple(map(str, items))) + '\n')

stop = time()
print(stop - start)

19651.745468854904